The crash happened on eastbound Roosevelt Road near Clark Street.
Chopper 7 was over the scene as first responders shut down the eastbound lanes of Roosevelt.
CTA's #12 Roosevelt, #18 16th/18th, and #192 U. of Chicago/Hospitals Express buses were rerouted due to the crash.
It was not immediately clear how many people were injured in the crash.
This is a developing story.
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