ISP said the four-vehicle crash happened just before3 p.m. in the inbound lanes near Halsted Street.
Chopper 7 was over the scene. Video shows a semi and a car that collided and went off the side of the road.
A person who was inside one of the vehicles involved was hospitalized for their injuries, ISP said.
The right lane was closed just after 3 p.m., and Chopper 7 video showed traffic getting by slowly.
Authorities did not immediately provide further information about the crash.