The semi crashed just around 12:27 a.m. on the northbound lanes of I-55 approaching Joliet Road and I-355 in Bolingbrook.
The semi struck a concrete median barrier and rolled over, according to ISP.
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Two left lanes were blocked as of 5:30 a.m., causing some long delays for morning commuters.
Chopper 7 was over the scene at 6:49 a.m., showing the lanes were still closed.
The backup was about six miles long.
The driver of the semi was taken to the hospital with injuries. His condition was not released.
The semi was hauling cauliflower.
No other vehicles were involved in the crash.