Chopper 7 was over the scene around 2:30 p.m. as firefighters worked to put out the flames at 1050 St. Charles Street.
Some flames could be seen inside two side-by-side structures at what appeared to be a property owned by Welch Brothers Construction Supply.
The fire also sent billows of smoke into the air.
There have been no reports of any injuries.
Further details, including what may have sparked the fire, have not been released.