The former president was invited to be a guest speaker in a conversation moderated by Bloomberg Editor-in-Chief John Micklethwait.
The event is hosted by The Economic Club of Chicago and Bloomberg News.
VP Kamala Harris was also invited to attend the event. Trump was the only one to confirm his attendance.
The one-hour program will begin at 11 a.m. The Club will livestream the conversation on YouTube.
On Monday, vice presidential candidate JD Vance was also in the Chicago area for a private fundraising event.
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Governor JB Pritzker issued the following statement on Trump's visit:
"Every time he opens his mouth, Donald Trump reminds us that he is a racist, misogynist 34-time convicted felon who doesn't care about anyone but himself. On a recent visit to Chicago, he spewed insults at Kamala Harris and no doubt we'll hear it again today as he tries to peddle his economic plans that would raise costs for American families by $4,000, spike inflation, and kill jobs. But a majority of Americans reject those policies and the other disastrous, dangerous Project 2025 proposals a second Trump administration would plague this country with. On November 5th, voters will make that very clear when we send Donald Trump and his MAGA extremism packing."