Pamela Johnson and her 43-year-old boyfriend were both hit at about 1:40 a.m. when crossing LSD near Ohio Street in the Gold Coast neighborhood, police said. The boyfriend told police that they were trying to escape a group of armed robbers.
The boyfriend survived and remains hospitalized Sunday.
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The driver of the pickup truck, which was headed southbound, spoke to police. No charges have been filed.
Chicago police are investigating and reviewing video from a nearby pod cam, as well as from several private businesses in the area.
Andrew Holmes, a relative, said he doesn't believe that robbers were involved and hopes surveillance video can help determine what happened.
Johnson was a single mother, leaving behind a 12-year-old son, Malik, family said.
She was a source of joy, family members said, sending money to a sister who was in college out-of-state.
"She'd do anything for anyone," said her grandmother Geraldine Johnson.