The resident is no longer considered a potential case, and no further public health action is needed, the CDC said.
Winnebago County includes Rockford, Illinois.
"The risk of getting Hantavirus remains very low for Illinois residents. The best way to protect yourself from Hantavirus and other rodent-borne diseases is by keeping rodents out of your home and cleaning up after them safely," the Illinois Department of Public Health said.
IDPH had said last week they were investigating a potential hantavirus case.
The North American strain of the hantavirus is not spread from person to person, IDPH said. It is different from the Andes strain associated with the MV Hondius cruise ship.
Orkin, a nationwide pest control company, says they have specific protocols in place when dealing with wildlife and rodent droppings to help mitigate potential spread.
Pest experts advise homeowners to spray disinfectant before sweeping rodent droppings away.
Illinois has had seven positive cases of hantavirus since 1993, most recently in March 2025.
Since surveillance began in 1993, the U.S. recorded 890 cases of Hantavirus over 30 years (1993-2023), IDPH said.
"The Illinois Department of Public Health (IDPH) has not been notified of any Illinois residents being passengers on the MV Hondius during the Hantavirus outbreak. IDPH will proactively update the public should there be any changes. While the risk to Illinois communities is currently very low, IDPH is coordinating closely with health care providers, local public health departments, and emergency management partners. IDPH will continue to monitor the situation closely and provide timely information to the public should there be any notable updates," the IDPH said.
The video in the player above is from an earlier report.