The crash happened at about 5:30 a.m. in the 1100-block of West Congress Parkway, police said.
Police said the unknown driver of a dark-colored Lincoln sedan was heading eastbound when it struck a median.
The 24-year-old victim was a passenger in the vehicle, police said.
She died at the hospital.
The Cook County Medical Examiner identified the victim as Lilia Perez of Chicago.
No other information was available.