The crash occurred at about 2:52 a.m. in the northbound lanes of I-94 at Tower Road in Glencoe.
Police said the crash involved a red Pontiac, Black Hyundai, white Jeep and a gray Tesla.
Illinois State Police originally said at least one female passenger was transported to the hospital with injuries.
On Monday, the Cook County Medical Examiner said Alejandro Fernandez, 32, died in the crash.
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Further details of the crash were not immediately available.