The driver was able to escape before an Amtrak train hit the vehicle.
The crash happened around 7:45 p.m. near River Drive and Lehigh Avenue in Morton Grove on the tracks which Amtrak shares with Metra.
The driver of an Acura had crashed into a parked car on Lehigh Avenue before driving onto the tracks, leading to the vehicle becoming disabled, police said. The 56-year-old man driving the Acura was arrested for DUI.
Metra's Milwaukee North Line was operating with delays as the tracks are anticipated to be closed overnight.
No one was seriously injured in the crash.