The crash occurred at about 5:50 a.m. in the 6800-block of North Sheridan Road.
Police said a 27-year-old man was driving northbound when he struck a 34-year-old male pedestrian on the street.
The victim was transported to St. Francis Hospital, where he was pronounced dead, police said.
No other injuries were reported. The driver of the SUV remained at the scene and no citations have been issued.