The crash happened around 5:17 a.m. in the northbound lanes of the Edens Expressway between Old Orchard Road and Lake Avenue.
Chopper 7 was over the scene around 6 a.m. where traffic could be seen backed up for a couple of miles in Skokie.
By 6:40 a.m. crews had the truck upright, but it lost its load in the crash. Chopper 7 was over the scene as crews cleaned up what seemed to be produce from the expressway.
By 7:30 a.m. the crash was all cleared out, but traffic was backed up for about one hour.
The extent of the driver's injuries is unknown. At least one person was taken by first responders.
What led up to the crash was not immediately available by authorities.
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