The school bus was involved in a crash with a vehicle around 1:22 p.m. near Howard Street and Lowell Avenue in Skokie, police said. The bus then crashed into a home in the 4300 block of Howard Street.
The school bus could be seen on the lawn of the home near the side of the building, and there was extensive damage to an exterior wall of the house.
A driver was the only occupant of the school bus and there were two adults inside the other vehicle involved in the crash, Skokie police said. They were all taken to local hospitals with minor injuries.
Residents were inside the house when the school bus crashed into it, but none of them were injured, police said.
First responders could be seen near the site of the crash. The passenger vehicle had frontal damage and could be seen loaded onto a tow truck.
No further information was immediately available.