Chicago police said the shooting happened in the Washington Park neighborhood's 200-block of East 57th Street just after 5 p.m.
A 35-year-old woman was inside a vehicle, headed eastbound on 57th Street, when someone standing near the street fired shots, striking her, police said.
Police said the victim was transported in critical condition to Stroger Hospital, where she later died.
There is no one in custody and Area One detectives are investigating.
Authorities did not immediately provide further information about the shooting.
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