Officers responded to the intersection of Route 83 and Lexington Drive at about 8:33 p.m. where they found a 2012 Chevrolet Equinox and a 2012 Chevrolet Silverado both heavily damaged after crashing in the intersection.
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The 41-year-old man who was driving the Equinox was pronounced dead at the scene. The Lake County Coroner's Office identified him as Epifanio Camarena of Round Lake. Preliminary autopsy results confirmed he died as a result of multiple blunt force injuries from the crash
Six people were transported to Advocate Condell Medical Center in critical condition, according to a battalion chief with the Greater Round Lake Fire Protection District.
Five of those victims - four children, ranging in age from 4 to 15, and a woman - were riding together in the Equinox, police said.
Police said the woman and a 5-year-old were seriously hurt. A 14-year-old has been released from the hospital and the two other children appeared to be OK.
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Police said the pick-up truck driver was also injured in the crash, but did not share details on the extent of his injuries.
As police continue to investigate the cause, they said the pick-up driver has submitted to drug and alcohol testing.
No charges have been filed at this time.