Police say the fire that broke out around 1:27 a.m. caused heavy damage to the third floor of a building in the 2400 block of East 77th Street.
The 46-year-old man suffered burns to his hands according to police. He was taken to the hospital in good condition and is expected to be ok.
A warming bus was at the scene to help displaced residents stay warm.
The cause of the fire is under investigation.