At around 4:30 p.m., the driver of a Ford Expedition was travelling eastbound on 47th Street when he failed to come to a stop and ran a red light at South Halsted Street, colliding with a Chevy Equinox driven by a 61-year-old man.
The boys were passengers in the Equinox, police said. Both were transported to Comer Children's Hospital in critical condition.
No citations had been issued Monday evening.