The non-profit "Truth Initiative" studied almost 2,600 people who signed up for the service.
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It works by sending texts containing tailored advice, social support, and coping skills.
At the beginning of the year-long trial, all participants reported vaping within the last 30 days, with more than 82% saying they did so within 30 minutes of waking.
At the seven-month follow-up point, just 24% reported vaping during the previous month.
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The study did not include teens, which have the highest rate of e-cigarette use.
Results of the research were published in the Journal of the American Medical Association publication JAMA Internal Medicine.
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