Police said just before 2 a.m. that streets in the 2300-block of Barnhart Street in the Cornerstone Lakes subdivision were closed, as West Chicago fire crews responded to a structure fire.
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Later Saturday morning, fire crews found a "deceased victim" inside the home, police said.
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The person has not yet been identified, pending notification of next of kin.
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Parts of Barnhart Street and Bainbridge Boulevard remained closed, as officials investigate.
The public is asked to avoid the area.