Executive producers Barbara Walters and Bill Geddie said in making Monday's announcement that it will mark the first time a sitting U.S. president has visited a daytime talk show.
Obama's interview will touch on topics including jobs, the economy, the Gulf oil spill and family life inside the White House. It is scheduled to be taped on Wednesday.
Obama was a guest on "The View" as a U.S. senator in March 2008.
Walters will make a special return to the studio to join her co-hosts for the occasion. She has been off since undergoing open-heart surgery in May and had not planned to be back until September.
"The View" airs weekdays on ABC7 at 10 a.m. Chicago time.