The former third baseman and radio broadcaster died last December.
Santo's statue is under wraps right now, but it will be near the Billy Williams statue outside the right field gate at Wrigley Field.
Among the guests of honor expected for the unveiling are Ernie Banks, Billy Williams, Glenn Beckert, Randy Hundley, Fergie Jenkins, and Milt Pappas, as well as members of the Santo and Ricketts families.