The incident happened at approximately 11 p.m. near 63rd Street and Eberhart.
Police say they approached a group of people to conduct an interview when a man ran away with his hand in his waistband. After a chase, police say the man refused to remove his hand from his waistband. A police spokesman says an officer feared for his own safety and shot the man.
The man was rushed to a hospital. His identity and condition had not been released early Sunday.
The Independent Police Review Authority says it is investigating.