The photo shows a white Dodge Ram quad cab with a black tailgate.
The truck was last seen near 79th Street and Martin Luther King Drive. That's just blocks from where police said the truck's driver hit 58-year-old Cassandra Holmes on Wednesday.
Holmes is the sister of well-known community activist Andrew Holmes, who said his sister's surgery has been postponed until the swelling in her knee goes down. She suffered two fractures and is still in a lot of pain, Andrew Holmes said.
RELATED: Chicago community activist Andrew Holmes' sister injured in hit-and-run on South Side
"I lost my older sister," he said, choking up, "I didn't want to lose my baby sister."
Andrew Holmes' daughter was also a victim of violence. She was shot and killed in Indianapolis in 2015.
Anyone with information on the incident is asked to call Chicago police at (312) 745- 4521.