The new musical features lots of his songs. ABC7's Janet Davies caught up with him before the show.
"The great thing to me about it is as much time, in the days when nobody knew who I was when I first started playing Chicago I found my audience here. I owe this city a lot and I'm so glad we could bring this show here. It's on the way to Broadway. I couldn't be happier," Buffett said.
The production has been mounted in a few other cities before Chicago, but Chicago has the distinction of sending it off to the Great White Way.
"Escape to Margaritaville" runs through Dec. 2.