Prodigy co-founder Liam Howlett said in an Instagram post that Flint killed himself over the weekend.
"I'm shell shocked ... confused and heart broken," he wrote.
It is with deepest shock and sadness that we can confirm the death of our brother and best friend Keith Flint. A true pioneer, innovator and legend. He will be forever missed.— The Prodigy (@the_prodigy) March 4, 2019
We thank you for respecting the privacy of all concerned at this time. pic.twitter.com/nQ3Ictjj7t
Police confirmed that the body of a 49-year-old man had been found at a home in Brook Hill, northeast of London. They said the death was being treated as non-suspicious and a file would be sent to the coroner - standard practice in cases of violent or unexplained deaths.
Flint was the stage persona of the band, whose 1990s hits "Firestarter" and "Breathe" were an incendiary fusion of techno, breakbeat and acid house music.
He was renowned for his manic stage energy and distinctive look: black eyeliner and hair spiked into two horns.
"A true pioneer, innovator and legend," the band said in a statement confirming his death. "He will be forever missed."
The Prodigy sold 30 million records, helping to take rave music from an insular community of party-goers to an international audience. They had seven No. 1 albums in Britain, most recently with "No Tourists" in 2018.
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The band attracted criticism for the 1997 single "Smack My B**** Up," and the accompanying sex- and drug-fueled video. The National Organization for Women accused the song of encouraging violence against women, and it was banned by the BBC.
The band denied misogyny, pointing out that the song's protagonist is revealed in the video to be a woman.
Born Keith Charles Flint on Sept. 17, 1969 in east London, he moved to east of the city to Braintree, Essex as a child, where he met Howlett at a nightclub.
The Prodigy was formed in the early 1990s, with Howlett as producer and Flint originally employed as a dancer before becoming singer and the onstage focal point.
The band's rise coincided with soul-searching in Britain over electronic dance music and its related drug culture, and the Prodigy became known as much for its anti-establishment stance as for its songs. The band members were vocal critics of the U.K.'s Criminal Justice and Public Order Act 1994, which banned the raves popularized in the late-1980s during the so-called Second Summer of Love.
Electronic duo the Chemical Brothers tweeted that Flint "as an amazing front man, a true original and he will be missed."
Grime musician Dizzee Rascal said he had opened for The Prodigy in 2009, "and he was one of the nicest people I've met and always was every time I met him, the whole band were. When it comes to stage few people can carry a show like him I'm proud to say I've seen it for myself."