The Biden Administration is now urging the Canadian government to use its power and intervene to end the truck blockade along the border.
Car companies are being forced to stop production because they're not getting parts from Canada.
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Ford said it may have to airlift auto supplies into the country.
In recent days, truckers protesting vaccine mandates in Canada have forced authorities to close the Ambassador Bridge, which links Detroit and Windsor, Ontario - a crucial transit point for moving auto parts and other supplies.
"They are blocking off and choking the economies of both the United States and Canada," said Windsor Mayor Drew Dilkens.
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Car companies have been forced to halt or scale back production.
Now, Dilkens is seeking a court injunction that would allow police to "physically" move in and end the blockade.
"If we can't gain compliance, then we bring tow trucks in and many police services to help remove people who are illegally blocking the roadway," the mayor said.
Demonstrators also forced the closure of two other border crossings. One connecting Manitoba and North Dakota, the other between Alberta and Montana.
It comes as demonstrators paralyze Canada's capital as the protests in Ottawa enter a third week.
The blockade at the border is yet another threat to the auto industry, which is already struggling from supply-chain issues and a shortage of semiconductors.
New numbers show consumer prices in the U.S. rose 7.5% last month compared to the same time a year ago, marking the worst inflation since 1982 and soaring car prices account for nearly a quarter of that inflation.