Gunfire erupted after two men were involved in a crash on Westheimer and South Kirkwood just before 2:45 p.m.
Eyewitness News reporter Erica Simon was at the scene preparing for a story when the sound of gunshots filled the air.
"We look around and see a shootout in the middle of the street," Simon wrote on Twitter. "Bullets flying everywhere. I just ducked and prayed."
EYEWITNESS VIDEO: Suspect opens fire on Westheimer
Simon says a woman was injured in the crossfire as both suspects fired on one another.
An off-duty EMT rushed to help the woman, who had a bullet graze her head.
RAW VIDEO: Two men face each other with guns drawn after an accident on Westheimer
One of the suspected shooters was placed into an ambulance and taken to Ben Taub Hospital with a gunshot injury. The second shooting suspect is in police custody.