Investigators say a 2004 black Buick LeSabre is missing from the home. The license plate number is V617710.
Firefighters responded to a home in the 10800-block of South Morgan Street around 12:40 a.m. Monday and found the house fully engulfed by flames. The force blew out the windows and left a huge hole in the one-story home.
The death is being investigated as a homicide and the fire appears "suspicious," officials said. Fire detectives said natural gas was not a factor and the case is being investigated as possible arson.
The body was badly burned and has not been positively identified.
PHOTOS: House explosion, fire in Morgan Park neighborhood