The run started at 9 a.m. at Montrose Harbor, 601 W. Montrose Ave. Mayor Lori Lightfoot is stopped by the 5K, 10K, and Half Marathon to congratulate runners as they crossed the finished line.
More than 2,200 are expected to run in this year's race.
This race is unique; it led the nation in creating a more inclusive event by including a non-binary gender category for people to choose during registration.
Proud to Run has donated more than $600,000 to organizations that support the Chicagoland LGBTQ+ community
Saturday's races will lead up to the 50th Annual Pride parade, "Stonewall 50: Millions of Moments of Pride." It will step off at 12 p.m. on Sunday. The parade will also be broadcast on ABC7 at 1 p.m.