Officers swarmed the home in the 300-block of East 76th Street in the city's Gresham neighborhood around 10 a.m. People who lived near the home were evacuated as a precaution.
A 23-year-old woman managed to get out of the house unharmed, police said. She told authorities that a 27-year-old man was stilled holed up inside.
When officers entered the home around noon, it was empty.
No one is in custody.