CPD and Chicago fire crews responded just after 8:15 p.m. Wednesday to the 800-block of West Buena Avenue for a reported residential fire.
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When they arrived, they found a 62-year-old man inside unresponsive, CPD said.
He was taken to Weiss Hospital, where he was pronounced deceased.
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Officials believe he may have suffered from smoke inhalation.
The man was not immediately identified.
Chicago fire officials said the smoke alarm in the apartment was not working, and the fire appeared to have started in the kitchen.
CFD said the apartment had a history of calls for "cooking issues."