A 21-year-old man was driving a Nissan east in the 400-block of West 87th Street just before 6:45 a.m. when he hit a bus that was making a left turn from 87th Street, CPD said.
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The bus then hit a nearby fence.
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Three occupants on the bus, an 18-year-old man, a 19-year-old man and a 40-year-old woman were taken to St. Bernard Hospital in good condition.
The driver of the Nissan was taken to Jackson Park Hospital in good condition.
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The female bus driver refused treatment.
No citations had been issued later Wednesday morning.