The White Sox begin the 2021 season against the Los Angeles Angels on April 1. The White Sox will play their home opener on April 8 against the Kansas City Royals.
The Cubs will begin their season at home against the Pittsburgh Pirates on April 1.
RELATED: Chicago White Sox, Cubs announce 60-Game 2020 season schedule, Opening Day July 24
The White Sox and Cubs will play each other from August 6-8 at Wrigley Field and from August 27-29 at Guaranteed Rate Field.
The schedule announcement for 2021 comes less than a week after the 2020 schedule was announced. The 2020 MLB season has been shortened to 60 games due to COVID-19.
For the full White Sox 2021 schedule, click here. For the full 2021 Cubs schedule, click here.