Flames shot through the roof at Nipsey's Restaurant and Lounge, located at 9156 S. Stony Island Ave., and firefighters attacked the blaze from multiple sides just after 6 a.m.
It was put out just before 7 a.m. No one was reported injured, according to CFD.
RELATED: Albany Park fire guts Twisted Hippo brewpub, gym, apartment building; 1 injured
Firefighters remained on the scene, and some roads were closed in the area, including 91st Street and Stony Island Avenue.
A Chicago Police Department spokesman said the building's roof collapsed.
It was not immediately clear how the fire began or how extensive the damage to the business was later Monday morning.