The incident occurred just before 1:50 a.m. in the 5600-block of South Nottingham Avenue, according to Chicago police.
The incident involves a Chicago police officer.
RELATED: Rogers Park shooting: Shootout with Chicago police injures 5, 1 critically: CFD
The officer suffered facial injuries and was taken to MacNeal Hospital in Berwyn, sources say.
Area One detectives are investigating the circumstances surrounding the incident, which appears to be domestic-related, Chicago police said.
Police said later Wednesday morning that the relationship between the officer and man killed was father and son.
Five people were injured, one critically, in a shootout with Chicago police in Rogers Park Tuesday night, fire officials said.