It happened Friday evening around 6:10 p.m. in the 600 block of W. 71st Street in the city's Englewood neighborhood.
Chicago police: 5 shot, 1 fatally, in Fuller Park; teen killed identified
Police said the victims were in a car when someone in another vehicle that pulled up alongside them opened fire.
A 27-year-old man was shot in the back and transported to the University of Chicago Hospital in good condition. A 32-year-old woman was shot in the right leg and taken to University of Chicago Hospital in good condition.
Two children of unknown age were also in the vehicle but not hurt. They were both transported to Comer Children's Hospital for observation, according to police.
Area One Detectives are investigating.