CPD responded about 12:15 a.m. to the 1000-block of East Marquette Road and found the boy lying on the ground.
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He had been shot multiple times in the stomach and died in the street, Chicago police said.
Witnesses said they saw a blue minivan take off after the shooting.
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CPD did find a weapon at the scene.
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There was no one in custody later Thursday morning. Area One detectives are investigating.
There have been 171 juveniles shot this year, including 26 homicides.