The 26-year-old was on the Kedzie-Homan platform in the 500-block of South Kedzie Avenue about 5 a.m. and got into a verbal altercation with a female suspect, police said.
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The suspect pulled out a knife and stabbed the man in the right side of the chest before fleeing, CPD said.
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The man was cut and taken to Mount Sinai Hospital in fair condition.
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No one was in custody later Thursday morning, and Area Four detectives are investigating.
O'Hare-bound Blue Line trains were running with some delays after the incident, the CTA tweeted just before 5 a.m.