The crash happened around 4:15 p.m. in the 3300 block of South King Drive, Chicago police said.
Investigators said a female, whose age was not yet known, was riding a scooter southbound when she was struck by a Jeep also heading south.
The victim was taken to the University of Chicago Hospital, where she was pronounced dead, police said. Her identity has not yet been released.
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The driver remained on scene and was cited for failure to avoid the crash, CPD said.
No further information was immediately available.