The shooting happened around 3:30 a.m. on Tuesday in the 1600-block of Howard Street in the Rogers Park neighborhood, police said.
Officers responded to calls of a shooting and found a 38-year-old man on the ground.
The victim had a gunshot wound to the back of the head. He died at the scene.
The man's identity was not immediately available.
No one in custody. CPD Area Three Detectives are conducting a homicide investigation.
Howard was closed between Marshfield and Paulina as officers continued their investigation.
CTA rerouted the southbound #147 Outer DuSable Lake Shore Drive express buses as a result of the closure.
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