The demonstration has been on the quad since April 30. Organizers of the encampment want the university to be transparent about investments in Israel.
The protesters have called for a ceasefire in Gaza.
Chicago alderman Byron Sigcho-Lopez was on campus Saturday night, supporting the demonstrators.
DePaul's president said in a letter that he believes students set up the encampment with "sincere intentions to peacefully protest," but he says they've "inadvertently" created public safety issues.
READ MORE | DePaul University pro-Palestinian encampment draws counter-protesters