The rollover crash happened on Sunday at about 5:46 p.m. on I-57 north of 147th Street in Harvey, police said.
Six-month-old Dakari Lomax of Chicago died in the crash, according to the Cook County Medical Examiner's Office.
Latasha M. Hope, 33 of Hazel Crest, was charged with his death.
Illinois State Police said Hope was driving the red Ford SUV with a female passenger, four toddlers and baby Dakari.
Police said none of the children were wearing seat belts or were in their car seats.
Hope was charged with reckless homicide, aggravated driving under the influence and child endangerment resulting in death.
No other information was available.
The video in the player above is from a previous report.