ISP said the multi-vehicle crash happened in the westbound lanes of I-80 west of Interstate 55 near Shorewood just after 7 a.m.
A semi hit a car, which had already crashed in a lane, ISP said. The wreckage also appeared to involve multiple boats that were being towed.
A pedestrian was fatally hit while standing outside of her vehicle.
All westbound lanes of I-80 are closed, and traffic is being diverted onto I-55 northbound. Police said there is not estimate as to when lanes will reopen.
Police did not immediately provide further information about the crash.
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