The hospital said it will still offer emergency services for pediatrics, but further care will be handled by Edward Hospital in Naperville.
In a statement, the medical center says the change is being made to expand other needed critical service lines.
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"Our mission remains unchanged: to best serve our communities evolving needs and provide high-quality, patient-centered care to every individual and family we serve," Prime Healthcare said.
The statement said there has been a decline in demand for inpatient pediatric services, and the need for advanced surgical, neurosurgical and spinal care has grown.