Thomas Tansey, 30, faces a count a first-degree murder in the death of 23-year-old Kenneth Paterimos, according to state's attorney's office spokeswoman Aviva Bowen.
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The charges come after Chicago police said they were questioning a person of interest Wednesday.
Paterimos was killed outside Richard's Bar in the 400 block of North Milwaukee Avenue on February 21.
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Police had said Paterimos had gotten into an argument with a 30-year-old man just before midnight. Paterimos was then stabbed several times in the arm, neck, and back, according to police.
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Last week, a Cook County judge issued a no-bail arrest warrant for Tansey, but he wasn't in police custody until Wednesday.
Police had arrested the 30-year-old at the scene but he was released without charges several days later.
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The charges come a day after family, friends and members of the community gathered outside Richard's Bar on Tuesday to call for justice in Paterimos' death.
Tansey is scheduled for a bail hearing on Thursday.
The Sun-Times Media Wire contributed to this report.