One semitrailer rear-ended another just after 5 a.m. on Interstate 94 near Illinois Route 176 in Lake County, ISP said.
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One driver was injured, police said.
The right lane was shut down until the vehicles could be towed.
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Neither how the crash occurred nor the driver's condition was immediately clear in the incident near Libertyville.
Chopper 7 was over the crash about 6 a.m., and a massive backup was visible.