The Chicago Fire Department received a call just after 9:20 a.m. of smoke coming from a building near 67th Street and Cregier Avenue.
While crews were looking for the fire, they pulled down on the ceiling and it fell on top of them, fire officials said.
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Three firefighters were transported to University of Chicago Medical Center in serious condition.
At around 3:30 p.m., the department said that two of the firefighters were released back to active duty. The third firefighter was put on medical leave, according to CFD officials.
This is a developing story; check back with ABC 7 Chicago for updates.