Chopper 7HD was over the scene at Mannheim Road and Lake Street. That intersection is right on the border of Melrose Park and Stone Park.
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Part of what appears to be a pickup truck was totally destroyed in the crash, which involved a UPS semi-truck.
ABC7 is working to find out if anyone was hurt, and to get more details on what may have caused the crash.
This is a developing story. Check back with ABC7 for updates.