Authorities responded to a fire in a three-story apartment building in the 6500-block of North Ashland Avenue at about 8:47 p.m.
A 79-year-old woman was found in the basement and rushed to St. Francis Hospital, where she was pronounced dead, police said.
She was later identified as Bertha Torres by the Cook County Medical Examiner's Office.
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The cause of the fire remains under investigation.