Police said the shooting happened in the Bronzeville neighborhood near South Dearborn Street and West Root Street just before 3:40 p.m. Chopper 7HD was over the scene.
SEE ALSO | Chicago shooting: Man charged with opening fire on CPD officers in Englewood, officials say
A 15-year-old boy was walking on the sidewalk when an SUV pulled up and someone inside opened fire, striking him in the back, police said. The teen was transported to Comer Children's Hospital in serious condition.
No one is in custody and Area One detectives are investigating.
Officials did not immediately provide further information about the shooting.
INTERACTIVE SAFETY TRACKER Track crime and safety in your neighborhood